bs-0012M [Primary Antibody]
alpha/beta Synuclein Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Mouse

Target Protein: alpha + beta Synuclein

Immunogen Range: 122-140/140


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6622

Swiss Prot: P37840

Source: KLH conjugated synthetic peptide derived from human Alpha-Synuclein

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Background:

May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

Size: 100ul

Concentration: 1ug/ul

Applications: ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 14


Cross Reactive Species: Mouse
Rat

Predicted Cross Reactive Species: Human
Dog
Cow
Sheep
Pig
Horse
Guinea Pig

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Wenxiang Fan. et al. S-oxiracetam Facilitates Cognitive Restoration after Ischemic Stroke by Activating 7nAChR and the PI3K-Mediated Pathway. 2021 Jan 22Read more>>
  • Qing Guan. et al. Single-cell RNA sequencing of CSF reveals neuroprotective RAC1<sup>+</sup> NK cells in Parkinson's disease.. FRONT IMMUNOL. 2022 Sep;13:992505-992505Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin-embedded rat brain labeled with Mouse Anti-Alpha-Synuclein Polyclonal Antibody, Unconjugated(bs-0012M) 1:200, overnight at 4°C, The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated(bs-0295G-Cy3)used at 1:200 dilution for 40 minutes at 37°C.


Formalin-fixed and paraffin embedded rat brain labeled with Mouse Anti-α-Synuclein Polyclonal Antibody, Unconjugated (bs-0012M) at 1:200 followed by conjugation to the secondary antibody and DAB staining